Searching for Evidence Based Literature in Medline via Ovid

welcome to the evidence-based searching class in this portion of the online class I will demonstrate how to do an evidence-based search in Ovid MEDLINE the first thing that you'll want to do is to go to the wapis library homepage and click on the link for electronic resources if you scroll down you'll notice that MEDLINE via Ovid is one of our core resources so you can click on the link here as you'll notice we have several different Ovid MEDLINE to choose from I generally recommend using the first since it covers 1950 to the present and you can always limit your date range later I'm gonna click on the link for the database right now and here is Ovid MEDLINE it's recommended that if you're not familiar with searching MEDLINE via Ovid that use check out our help sheet and tutorials page and complete that tutorial first for this example we are gonna use the search that I mentioned in the introductory video for this class a 45 year old woman comes to your office she is suffering from clinical depression that is strongly opposed to taking prescription medications she wants to know if santa john's wort is as effective as traditional antidepressants for treating her symptoms we've already done the pica for this question so we know that for P we have a forty-five years old woman and depression for our eye we have sant john's wort our c is traditional antidepressants and our oh is decrease in symptoms of depression we need to break our search down into concepts so that we can take advantage of subject searching and Ovid's MEDLINE I recommend starting with the disorder or the disease first when you do your search so we're going to go back to Ovid MEDLINE and I'm going to start by searching for depression I'm going to go ahead and explode so that I'm including as many different types of depression as possible and I'm going to click on the continue button in this case we're interested in st. John's work for the treatment of depression so I'm going to pick drug therapy from the left side of the screen and then click on continue we now have our search for depression with drug therapy if you remember we're also looking at st. John's as a possible treatment so I'm going to go ahead and put sant john's wort into the search box notice that i have not used a period after the saint or an apostrophe between the end and the s that is because most databases do not like the use of non alphanumeric characters in the search box we'll go ahead and click on the search button and we see that our term has been mapped to Hypericum we could look at the scope note to make sure that's correct but I already know that hey Pierre come is the scientific name for Saint John's wort will click on explode in case there are different types of Hypericum and continue we're given an option to pick subheadings for Hypericum since I've already selected the subheading for drug therapy with depression I will not choose therapeutic use with Hypericum this is just my opinion there are of course different ways to search and none of them are completely incorrect we'll click on continue and the other part of our search of course was that we wanted to compare Hypericum with traditional antidepressants so I'm going to come to my search box and put in anti depressants and then click on the search button you'll notice our term is mapped from antidepressants to anti-depressive agents that's okay we're going to click on explode and then click on continue again we do have options for subheadings but I already used my subheading with depression so I'm not going to use it at this point I'm going to just click on continue we have our three terms we can look back at our Pico to make sure we've gotten them all so we know we have trans st. John's wort traditional antidepressants and depression we do need to keep in mind that we have 45 years old and woman as other limits for our search but as I just said their limits so we're going to wait until the very end to apply this go back to Ovid MEDLINE and I want articles that talk about all three of these topics so I'm going to check the boxes to the left and click on and we come up with 75 results we now want to make sure that we're looking at articles to discuss women in the correct age range because we want to deal with articles similar to our patient we have some limits here and are frequently used limits but I'm gonna go down here and click on the additional limits button on this screen we have several different limits to choose from two limits that I almost always apply our English language which you can see here in the middle and humans since we want clinically relevant information if you scroll down the page you see that we have our age groups in this example our patient is 45 years old so we're gonna scroll down and find the best age range to suit her in this case middle age starts at 45 so we'll get that but since she's only 45 she's kind of on the cusp I might go ahead and select adults as well we also know that our patient is a female so we're going to come down to our check tags and we can select female from the drop box gonna scroll back to the top of the page and click on the limit a search button as you can see we've gone from 75 results down to 18 just by limiting to female and the appropriate age range we could go through these one by one to see which ones were considered evidence-based or we can limit the search further I'm going to scroll down and limit the search more so I'm going to click on that additional limits button again at this point you may want to open the document that I've labeled limits handout from the evidence-based searching online class page if you scroll down we're going to pick the box that says publication types and from this box we're going to select the appropriate publications there are two ways to do this we could start at the top of the pyramid with meta-analysis limit the search see if we have any of those and if we don't move down the pyramid to systematic review and so forth and so on when you're first getting started with evidence based searching you may want to just limit to any of the evidence-based literature publication types and then go through and try to pick the strongest evidence afterwards that's what I'm going to do today so I'm gonna click on case reports and then hold the ctrl button on my keyboard so that I can select more than one I'll get clinical trial all clinical trial controlled clinical trial guideline which is a lower level of evidence but still considered evidence-based sometimes meta-analysis practice guideline randomized control trial and that's all if I didn't find any in these subject or in these publication types I might go back and limit to review but since it's a really low level of evidence I'm not going to do it at this point so scroll over the top of the page and click on limit a search we've gone from 18 articles down to 16 which is it a reasonable amount to go through this concludes the portion of the class that deals with finding evidence based literature within MEDLINE via Ovid there are other databases that are used often and you can find videos for those on the online evidence-based searching class page

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